PUBLICATIONS

Here you will find recent publication of Diana Pauly and her group members about complement system in vision research.

GLIOSIS-DEPENDENT EXPRESSION OF COMPLEMENT FACTOR H TRUNCATED VARIANTS ATTENUATES RETINAL NEURODEGENERATION FOLLOWING ISCHEMIC INJURY.

Josef Biber, Yassin Jabri, Sarah Glänzer, Aaron Dort, Patricia Hoffelner, Christoph Q. Schmidt, Oliver Bludau, Diana Pauly, Antje Grosche

2024, Journal of Neuroinflammation

NMOSD IGG IMPACT RETINAL CELLS IN MURINE RETINAL EXPLANTS

Hannah N Wolf, Veronika Ehinger, Larissa Guempelein, Tania Kuempfel, Joachim Havla, Diana Pauly

2023, Current Issues in Molecular Biology

We have added the most important results and take aways in a short blog entry which you can find here.

AS IN REAL ESTATE, LOCATION MATTERS: CELLULAR EXPRESSION OF COMPLEMENT VARIES BETWEEN MACULAR AND PERIPHERAL REGIONS OF THE RETINA AND SUPPORTING TISSUES

Randy Zauhar, Josef Biber, Yassin Jabri, Mijin Kim, Jian Hu, Lew Kaplan, Anna M. Pfaller, Nicole Schäfer, Volker Enzmann, Ursula Schlötzer-Schrehardt, Tobias Straub, Stefanie M. Hauck, Paul D. Gamlin, Michael B. McFerrin, Jeffrey Messinger, Christianne E. Strang, Christine A. Curcio, Nicholas Dana, Antje Grosche*, Mingyao Li*, Dwight Stambolian* and Diana Pauly*

2022, Frontiers in Immunology

*These authors share senior authorship.

COMPLEMENT FACTOR H-RELATED 3 ENHANCED INFLAMMATION AND COMPLEMENT ACTIVATION IN HUMAN RPE CELLS

Schäfer N, Rasras A, Ormenisan D, Amslinger S, Enzmann V, Jägle H, Pauly D.

2021, Frontiers in Immunology

A FAMILY AFFAIR: ADDRESSING THE CHALLENGES OF FACTOR H AND THE RELATED PROTEINS.

Poppelaars F, Goicoechea de Jorge E, Jongerius I, Baeumner AJ, Steiner MS, Józsi M, Toonen EJM, Pauly D; SciFiMed consortium.

2021, Frontiers in Immunology

SODIUM IODATE-INDUCED DEGENERATION RESULTS IN LOCAL COMPLEMENT CHANGES AND INFLAMMATORY PROCESSES IN MURINE RETINA.

Enzbrenner A, Zulliger R, Biber J, Pousa AMQ, Schäfer N, Stucki C, Giroud N, Berrera M, Kortvely E, Schmucki R, Badi L, Grosche A, Pauly D, Enzmann V.

2021, International Journal of Molecular Science

CELL-TYPE-SPECIFIC COMPLEMENT PROFILING IN THE ABCA4-/- MOUSE MODEL OF STARGARDT DISEASE.

Jabri Y, Biber J, Diaz-Lezama N, Grosche A, Pauly D.

2020, International Journal of Molecular Science

PROPERDIN MODULATES COMPLEMENT COMPONENT PRODUCTION IN STRESSED HUMAN PRIMARY RETINAL PIGMENT EPITHELIUM CELLS.

Schäfer N, Wolf HN, Enzbrenner A, Schikora J, Reichenthaler M, Enzmann V, Pauly D.

2020, Antioxidants

FASUDIL LOADED PLGA MICROSPHERES AS POTENTIAL INTRAVITREAL DEPOT FORMULATION FOR GLAUCOMA THERAPY.

Mietzner R, Kade C, Froemel F, Pauly D, Stamer WD, Ohlmann A, Wegener J, Fuchshofer R, Breunig M.

2020, Pharmaceutics

CELL-TYPE-SPECIFIC COMPLEMENT EXPRESSION IN THE HEALTHY AND DISEASED RETINA.

Pauly D, Agarwal D, Dana N, Schäfer N, Biber J, Wunderlich KA, Jabri Y, Straub T, Zhang NR, Gautam AK, Weber BHF, Hauck SM, Kim M, Curcio CA, Stambolian D, Li M, Grosche A.

2019, Cell Reports

OXIDATIVE STRESS INCREASES ENDOGENOUS COMPLEMENT-DEPENDENT INFLAMMATORY AND ANGIOGENIC RESPONSES IN RETINAL PIGMENT EPITHELIAL CELLS INDEPENDENTLY OF EXOGENOUS COMPLEMENT SOURCES.

Trakkides TO, Schäfer N, Reichenthaler M, Kühn K, Brandwijk RJMGE, Toonen EJM, Urban F, Wegener J, Enzmann V, Pauly D.

2019, Antioxidants

FUNCTIONAL DETECTION OF BOTULINUM NEUROTOXIN SEROTYPES A TO F BY MONOCLONAL NEOEPITOPE-SPECIFIC ANTIBODIES AND SUSPENSION ARRAY TECHNOLOGY.

von Berg L, Stern D, Pauly D, Mahrhold S, Weisemann J, Jentsch L, Hansbauer EM, Müller C, Avondet MA, Rummel A, Dorner MB, Dorner BG.

2019, Scientific Reports

COMPLEMENT COMPONENTS SHOWED A TIME-DEPENDENT LOCAL EXPRESSION PATTERN IN CONSTANT AND ACUTE WHITE LIGHT-INDUCED PHOTORECEPTOR DAMAGE.

Schäfer N, Grosche A, Schmitt SI, Braunger BM, Pauly D.

2017, Frontiers of Molecular Neuroscience